Towards Understanding the Role of Microstructured Edible Scaffolds for Cultured Meat Production.
Cultured meat is an emerging technology to produce edible muscles using animal cells, scaffolds, and bioreactors, avoiding the slaughter of farmed animals. In this work, an edible scaffold (film) with parallel microchannels formulated with marine biopolymers was made. The effect of parallel microchannels on the behavior of muscle cells and gene expression involved in fusion and myogenesis were assessed.
- D. Bezjak, N. Orellana, J. H. Valdés, T. Corrales & C. A. Acevedo
- Food and Bioprocess Technology
- Publicado en linea: 14 July 2023
- 10.1007/s11947-023-03166-2

Nanostructured electrochemical sensor applied to the electrocoagulation of arsenite in WWTP effluent.
A sensitive electroanalytical method for the determination of arsenite, based on a heterostructure of aminated multiwalled carbon nanotubes and gold nanoparticles, was applied in an electrocoagulation (EC) treatment for the elimination of arsenite.
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S. Piña, M. A. Sandoval, P. Jara-Ullo, D. Contreras, N. Hassan,
O. Coreño, R. Salazar - Chemosphere
- Volume 306, November 2022, 135530
- 10.1016/j.chemosphere.2022.135530

Expression of Hv1 proton channels in myeloid-derived suppressor cells (MDSC) and its potential role in T cell regulation.
The immunosuppression by MDSC is conditional to their ability to decrease the proton concentration elevated by the NOX2 activity, rendering Hv1 a potential drug target for cancer treatment.
- J. Alvear-Arias, C. Carrillo, J. P. Villar, R. Garcia-Betancourt, A. Peña-Pichicoi, A. Fernandez, M. Fernandez, E. M. Carmona, A. Pupo, A. Neely, O. Alvarez, J. Garate, H. Barajas-Martinez, H. P. Larsson, A. Lopez-Rodriguez, R. Latorre, C. Gonzalez
- PNAS
- Volume 19, April 2022, e2104453119
- 10.1073/pnas.2104453119

Spider Toxin SNX-482 Gating Modifier Spontaneously Partitions in the Membrane Guided by Electrostatic Interactions.
Spider toxin SNX-482 is a cysteine-rich peptide that interferes with calcium channel activity by binding to voltage-sensing domains of the CaV2.3 subtype.
- G. Mellado, N. Espinoza, J. Garate, A. Neely
- Membranes
- Volume 12, June 2022, 595
- 10.3390/membranes12060595

Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
In neurosecretion, allosteric communication between voltage sensors and Ca2+ binding in BK channels is crucially involved in damping excitatory stimuli. Nevertheless, the voltage-sensing mechanism of BK channels is still under debate.
- W. Carrasquel-Ursulaez, I. Segura, I. Díaz-Franulic, Valeria Márquez-Miranda, Felipe Echeverría, Y. Lorenzo-Ceballos, N. Espinoza, M. Rojas, J. A. Garate, E. Perozo, O. Alvarez, F. D. Gonzalez-Nilo, R. Latorre
- PNAS
- Volume 119, June 2022, e2204620119
- 10.1073/pnas.2204620119

On the effects of induced polarizability at the water–graphene interface via classical charge-on-spring models.
In this work, we have systematically studied, via molecular dynamics, two polarizable graphene models, denominated CCCP and CCCPD, employing the charge-on-spring model of the GROMOS forcefield, both being compatible with the polarizable water models COS/G2 and COS/D2, respectively
- Y. Escalona, N. Espinoza, M. Barria-Urenda, C. Oostenbrink, J. A. Garate
- Physical Chemistry Chemical Physics
- Volume 24, June 2022, 7748
- 10.1039/D1CP05573A

Optimization of N-PERT Solar Cell under Atacama Desert Solar Spectrum
In this work, we determined geometrical and doping parameters to optimize the power of an n-type bifacial passivated emitter and rear totally diffused solar cell (n-PERT).
- P. Ferrada, A. Marzo, M. Ruiz Ferrández, E. Ruiz Reina, B. Ivorra, J. Correa-Puerta, V. del Campo
- Nanomaterials
- Volume 12, October 2022, 3554
- 10.3390/nano12203554

Aquaporin Gating: A New Twist to Unravel Permeation through Water Channels.
The study of AQPs in their native membrane or overexpressed in heterologous systems have experimentally demonstrated that water membrane permeability can be reversibly modified in response to specific modulators.
- M. Ozu, . J. Alvear-Arias, M. Fernandez, A. Caviglia, A. Peña-Pichicoi, C. Carrillo, E. Carmona, A. Otero-Gonzalez, J. A. Garate, G. Amodeo, C. Gonzalez
- International Journal of Molecular Sciences
- Volume 23, October 2022, 12317
- 10.3390/ijms232012317
